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Investing in Transformative Health Technology—featuring Deena Shakir

Breakthrough health tech is useless if it fails to meet people where they are, especially when it comes to underserved populations. So, how do we encourage VCs to invest in culturally competent digital health solutions? How do we direct capital in a way that promotes health equity for women and communities of color? <a href="https://deenashakir.com/" target="_blank">Deena Shakir</a> is Partner at <a href="https://www.luxcapital.com/people/deena-shakir" target="_blank">Lux Capital</a>, where she invests in transformative technologies improving lives and livelihoods. She is passionate about investing in women&#39;s health, digital health infrastructure, health equity and foodtech, and her portfolio includes notable startups like Maven Clinic, Everly Health and Gameto. On this episode of HLTH Matters, Deena joins host Dr. Jessica Shepherd to discuss the fertility and maternal health crises we face in the US and the $90 million Lux has invested to address these issues.Deena describes some of the category leading companies in the Lux health tech portfolio and explains how she thinks about putting women’s health at the forefront of research, technology and innovation. Listen in for insight on building technologies that meet people where they are and get Deena’s take on the future of the healthcare investment landscape. Topics Covered<ul><li>Deena’s journey to becoming a VC in health and wellness tech</li><li>The $90M Lux has focused on investing in women’s health</li><li>Deena’s insight on the fertility and maternal health crises we face in the US</li><li>The category leading companies in integrated women’s health in the Luxe portfolio</li><li>Putting women’s health at the forefront of research, technology and innovation</li><li>How the conversation around women’s health is changing among VCs</li><li>How innovation has improved coming out of the pandemic</li><li>Why women in leadership serve as champions for cultural competency in healthcare</li><li>How time spent with her founders lifts Deena up on a bad day</li></ul>  Connect with Deena Shakir<a href="https://www.luxcapital.com/people/deena-shakir" target="_blank">Deena at Lux Capital</a>  Connect with Dr. Jessica Shepherd<a href="https://www.hlth.com/" target="_blank">HLTH</a><a href="https://twitter.com/JShepherd_MD" target="_blank">Dr. Shepherd on Twitter</a><a href="https://www.linkedin.com/in/jessica-shepherd-md-mba-5ba9ab66/" target="_blank">Dr. Shepherd on LinkedIn</a> Resources<a href="https://health.google/" target="_blank">Google Health</a><a href="https://www.mavenclinic.com/" target="_blank">Maven Clinic</a><a href="https://www.everlyhealth.com/" target="_blank">Everly Health</a><a href="https://www.alifehealth.com/" target="_blank">Alife Health</a><a href="https://academic.oup.com/humupd/advance-article/doi/10.1093/humupd/dmac035/6824414?login=false" target="_blank">‘Temporal Trends in Sperm Count: A Systematic Review and Meta-Regression Analysis of Samples Collected Globally in the 20th and 21st Centuries’ in Human Reproduction Update</a><a href="https://www.gametogen.com/" target="_blank">Gameto</a><a href="https://www.migahealth.com/" target="_blank">Miga Health</a><a href="https://www.cityblock.com/" target="_blank">Cityblock Health</a><a href="https://www.waymarkcare.com/" target="_blank">Waymark</a><a href="https://twitter.com/annewoj23" target="_blank">Anne Wojcicki</a>

S3 Ep32: Investing in Transformative Health Technology—featuring Deena Shakir

Partner

How to Disrupt Healthcare (Responsibly)—featuring Ruby Gadelrab 

Healthcare is a $4 trillion industry just waiting to be disrupted. But because people’s lives are at stake, we must disrupt the space responsibly. And that’s why every digital health company needs clinical experts on their teams and advisory boards. Ruby Gadelrab is Cofounder and CEO of <a href="https://mdisrupt.com/" target="_blank">MDisrupt</a>, a health advisory platform on a mission to organize the world&#39;s digital health products by performance through clinically crowdsourced data generation. Ruby has created a two-sided marketplace that pairs domain experts in healthcare with digital health companies in desperate need of high quality, actionable expertise. On this episode of HLTH Matters, Ruby joins hosts Dr. Jordan Schlain and Dr. Jessica Shepherd to explain why there is so little clinical representation in digital health startups and how MDisrupt pairs health tech companies with the right expert at the right time. Ruby describes how MDisrupt vets clinicians to become part of its health expert network and discusses how clinicians are compensated for their time. Listen in to understand the benefits of a having a medical advisory board and learn how MDisrupt helps health tech innovators accelerate their path to market and drive adoption. Topics Covered <ul><li>Ruby’s take on what it means to disrupt healthcare responsibly</li><li>Why it’s crucial for health tech companies to have clinical expertise on their teams</li><li>How MDisrupt provides an on-demand health expert marketplace</li><li>Ruby’s vision for MDisrupt to organize the world’s digital health products by performance</li><li>How MDisrupt vets clinicians to become part of its health expert network</li><li>How clinicians are compensated for being part of MDisrupt</li><li>Why there is so little clinical representation in digital health startups</li><li>Why health tech companies without medical advisory boards struggle with adoption</li><li>How Ruby’s team pairs a health tech company with the right expert at the right time</li><li>The market insight that inspired Ruby to build MDisrupt</li><li>How to assess your current advisory board and align incentives appropriately</li><li>Leveraging digital health to support underserved populations</li></ul>   Connect with Ruby Gadelrab<a href="https://mdisrupt.com/" target="_blank">MDisrupt</a> Connect with Dr. Jordan Shlain &amp; Dr. Jessica Shepherd<a href="https://www.hlth.com/" target="_blank">HLTH</a><a href="https://twitter.com/DrShlain" target="_blank">Dr. Shlain on Twitter</a><a href="https://www.linkedin.com/in/drjordanshlain/" target="_blank">Dr. Shlain on LinkedIn</a><a href="https://twitter.com/JShepherd_MD" target="_blank">Dr. Shepherd on Twitter</a><a href="https://www.linkedin.com/in/jessica-shepherd-md-mba-5ba9ab66/" target="_blank">Dr. Shepherd on LinkedIn</a> Resources<a href="https://www.instacart.com/company/pressreleases/instacart-launches-instacart-health-a-sweeping-new-initiative-to-deliver-the-ingredients-for-healthier-living/" target="_blank">Instacart Health</a><a href="https://ouraring.com/" target="_blank">Oura Ring</a><a href="https://diabetes.org/tools-support/devices-technology/choosing-cgm" target="_blank">CGM Devices</a><a href="https://www.invitae.com/en" target="_blank">Invitae</a><a href="https://www.23andme.com/" target="_blank">23 and Me</a>

S3 Ep17: How to Disrupt Healthcare (Responsibly)—featuring Ruby Gadelrab 

CEO and Co-founder

How Much of Longevity Is Controllable?—featuring Melanie Goldey

Research has shown that less than 10% of longevity is based on genetics and 90% hinges on your lifestyle choices. But if you don’t have Bryan Johnson’s resources, how do you identify the gap between your chorological age versus your real age? And more importantly, how do you use that information to design a plan that will truly move the needle on helping you live healthier, longer? Melanie Goldey is CEO of <a href="https://tallyhealth.com/" target="_blank">Tally Health</a>, a biotech company developing science-backed tools for consumers to increase health span and extend longevity.  Melanie has an extensive background in technology and healthcare startups, and she is passionate about making longevity science accessible to consumers. On this episode of HLTH Matters, Melanie joins host Dr. Gautam Gulati to discuss the future of diagnostic markers and testing to optimize for the extension of both lifespan and health span. Melanie explains how Tally Health differs from prior iterations of real age measurement and describes how her team uses DNA methylation to develop personalized recommendations for its members. Listen in to understand the benefits of Tally Helth’s pro-longevity supplements and learn how to enhance longevity with small improvements to your diet, fitness, sleep, mental health and habits! Topics Covered<ul><li>How Tally Health is working to help consumers live healthier, longer</li><li>The 3 components of Tally Health’s consumer longevity offering</li><li>What differentiates Tally from prior iterations of real age measurement</li><li>How Tally uses DNA methylation to develop personalized recommendations</li><li>David Sinclair’s research on epigenetics and his information theory of aging</li><li>How much of longevity is based on genetics vs. lifestyle choices</li><li>How Melanie thinks about quick fixes vs. small lifestyle adjustments</li><li>The benefits of Tally Health’s pro-longevity supplements </li><li>How machine learning can improve specificity of Tally’s recommendations</li><li>The connections among diet, fitness, sleep, mental health and habits</li><li>What we might learn from Bryan Johnson’s biohacking experiences</li><li>Other markers Tally Health is studying (beyond DNA methylation)</li></ul>Connect with Melanie Goldey<ul><li><a href="https://tallyhealth.com/" target="_blank">Tally Health</a></li><li>Melanie on <a href="https://www.linkedin.com/in/melanie-goldey/" target="_blank">LinkedIn</a></li></ul>Connect with Dr. Jessica Shepherd &amp; Dr. Gautam Gulati<ul><li><a href="https://www.hlth.com/" target="_blank">HLTH</a></li><li>Dr. Shepherd on <a href="https://twitter.com/JShepherd_MD" target="_blank">X</a></li><li>Dr. Shepherd on <a href="https://www.linkedin.com/in/jessica-shepherd-md-mba-5ba9ab66/" target="_blank">LinkedIn</a></li><li>Dr. Gulati on <a href="https://twitter.com/drgautamgulati" target="_blank">X</a></li><li>Dr. Gulati on <a href="https://www.linkedin.com/in/gautamgulati/" target="_blank">LinkedIn</a></li></ul>Resources<ul><li><a href="http://www.hms.harvard.edu/agingresearch/" target="_blank">Harvard Aging Lab</a></li><li><a href="https://www.nature.com/articles/s41586-020-2975-4" target="_blank">David Sinclair’s Landmark Study on Longevity in Nature</a></li><li><a href="https://www.bryanjohnson.com/" target="_blank">Bryan Johnson</a></li></ul>

S4 E42: How Much of Longevity Is Controllable?—featuring Melanie Goldey

Innovations in Oral Health for Improving Systemic Health

Oral health plays a pivotal role in shaping your overall well-being – a critical connection often underestimated in healthcare. In this episode, Mariya Filipova, Chief Innovation Officer at CareQuest Innovation Partners, and Maria Ryan, Executive Vice President and Chief Clinical Officer at Colgate Palmolive discuss the importance of systemic health and the role of oral health in the overall well-being of individuals. Maria highlights the interconnection between oral health and overall well-being. She discusses the impact of oral conditions on systemic health, emphasizing the risks of infection and inflammation. She also talks about Colgate&#39;s approach to innovation and partnership to better understand the landscape and bring innovations to the dental profession and consumers. They focus on the prevention and early detection of oral diseases, which can significantly improve oral health. On the other hand, Mariya addresses the disparity in investments in oral-systemic health. She points out that while oral health spending is significant, early-stage startup investments in oral health are minimal compared to healthcare startup investments. CareQuest Innovation Partners aims to bridge this gap by emphasizing the established clinical connection between oral and systemic health and encouraging the healthcare community to recognize this untapped opportunity for investment and innovation. Stay tuned for an inspiring discussion on the connection between oral health and systemic health, and how entrepreneurs and startups can contribute to this transformative movement.  About Mariya Filipova:Mariya Filipova, MBA Chief Innovation Officer, CareQuest Innovation Partners. Mariya is a member of the CareQuest Institute leadership team and serves as chief innovation officer of CareQuest Innovation Partners, the for-profit affiliate of CareQuest Institute. In her role, she oversees innovation, incubation, and investment activities aimed at developing solutions that advance oral health access, equity and integration for underserved populations.  Formerly, Vice President of Innovation at Anthem Inc, Mariya led efforts in scaling emerging technologies and new business models to accelerate Anthem’s transformation to a digital-first enterprise. Mariya’s vision and leadership in these areas resulted in the development of several breakthrough solutions and programs including the $5 million XPRIZE Rapid COVID-19 Testing competition, in partnership with seven Blue Cross Blue Shield Plans, to identify and validate fast, frequent, cheap, and easy-to-use testing solutions for SARS-CoV-2 and Anthem’s Digital Data Sandbox —the largest, certified de-identified commercial data set About Maria Ryan:Maria Emanuel Ryan, DDS, Ph.D. is Executive Vice President and Chief Clinical Officer at theColgate-Palmolive Company where she provides oversight and leadership to dental and dermalclinical organizations, knowledge management, and scientific communications teams. Dr. Ryanpreviously served as Professor and Chair of the Department of Oral Biology and Pathology atStony Brook University where she was actively involved in teaching, clinical practice, andresearch. She is the Past President of the American Association for Dental, Oral, and Craniofacial Research (AADOCR) and has served on many academic and foundation boards. Dr. Ryan has received numerous awards including NIH National Research Service Awards and a Physician Scientist Award. She received an achievement award from the American Dental Association and was the first recipient of the Victress Health Award to recognize her educational and research efforts in the area of women’s health. Dr. Ryan is a nationally and internationally known speaker and author who has appeared on multiple media outlets to discuss the importance of oral health to overall health and wellbeing as well as the role of the dental professional in the provision of optimal overall health care. Things You’ll Learn:<ul><li>Oral health is an integral part of systemic health. </li><li>What happens in our mouth can have a significant impact on our overall health and well-being. From gum disease to oral cancers, understanding these connections is crucial for improving outcomes.</li><li>The disparity between oral health spending and investment in oral health startups is striking. There&#39;s a huge opportunity for innovators and entrepreneurs to address this gap.</li><li>Collaboration and partnerships are key to driving innovation in oral health. Colgate Palmolive and Carequest Innovation Partners both emphasize the importance of working with external partners to bring new solutions to the market. </li><li>If you&#39;re a startup looking to make a difference, reach out to these organizations for potential collaborations.</li></ul> Resources:<ul><li>Connect with and follow Mariya Filipova on <a href="https://www.linkedin.com/in/mfilipova/" target="_blank">LinkedIn</a>.</li><li>Visit CareQuest Innovation on their <a href="https://carequestinnovation.com/" target="_blank">Website</a>.</li><li>Email CareQuest Innovation Partners <a href="https://carequestinnovation.com/connect/" target="_blank">here</a>.</li><li>Connect with and follow Maria Ryan on <a href="https://www.linkedin.com/in/maria-ryan-91516310/" target="_blank">LinkedIn</a>.</li><li>Visit the Colgate-Palmolive <a href="https://www.colgatepalmolive.com/" target="_blank">Website</a>!</li></ul>

S4 E4: Innovations in Oral Health for Improving Systemic Health

Executive Vice President and Chief Clinical Officer

Chief Innovation Officer

Podcast

S3 Ep32: Investing in Transformative Health Technology—featuring Deena Shakir

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